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Last year, the drugmaker submitted an application for approving tirzepatide for the treatment of HFpEF and obesity to the European Medicines Agency (EMA) and plans to submit it to other regulatory agencies soon

These reports lack the controls needed to draw reliable conclusions

"Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist"

However, it is imperative to recognize that the safety and efficacy of Tirzepatide for individuals seeking weight loss without diabetes or pre-diabetes are still under investigation