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For the past three years, the story of GLP-1 weight-loss drugs has been one of breakthrough and dominance

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The compounded versions of the drug were originally sold to combat a brand-name shortage

A UNC Health endocrinologist explains the long-term effects on hunger and weight.

Semaglutide typically begins reducing appetite within three to five days of your first injection, though noticeable weight loss usually appears within two to four weeks as your body adjusts to the medication