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[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Safarzadeh Kozani P., Naseri A., Mirarefin S.M.J., Salem F., Nikbakht M., Evazi Bakhshi S., Safarzadeh Kozani P

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Clinical trials say this dual approach often leads to greater weight loss than using medicines that just work on GLP-1

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Tres receptores: GLP-1R + GIPR + GcgR

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Eli Lilly and Company (2026) Lillys triple agonist, retatrutide, delivered powerful weight loss in pivotal Phase 3 obesity trial

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Some patients may switch from Mounjaro to Wegovy if their clinician determines it is appropriate

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