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Purpose of Review This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2-i) and present guidance on management and recommendations on adjunctive tapering of insulin in patients with insulin-dependent diabetes mellitus, which we term de-insulinization. Recent Findings GLP1-RA and SGLT2-i are the principal classes of diabetes medications evidencing cardiovascular benefit

This is a year-over-year improvement of 30 percentage points, almost doubling after three years

Self-administering semaglutide injections at home requires proper technique, sterile handling, and knowledge of injection sites

As a Family Practice PA I've been preparing patients for this change for weeks

This guide breaks down how FSA/HSA for semaglutide works, whats covered, and how to save on GLP1 treatments.