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This "dual agonist" mimics the gut peptides glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
This term refers to how long a medication stays in your system after you have ceased to use it
Pioglitazone has lower PPAR agonism compared with rosiglitazone but has more profound effects on MASH, potentially mediated by the mitochondrial target of thiazolidinediones, specifically the mitochondrial pyruvate carrier
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