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2 This level of weight reduction is considered clinically meaningful and surpasses results from similar pharmacotherapies for weight management

Starting GLP-1 therapy only to stop it two months before trying to conceive may not provide a long enough treatment window to achieve meaningful results

For most users, the benefits of the medicationsuch as improved blood sugar control, weight loss, and reduced risk of cardiovascular eventsfar outweigh the potential for minor side effects

Extended Data Extended Data Table 1|
