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Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain

[12] [22] Patients with fibromyalgia typically experience a constellation of symptoms beyond pain, including: Chronic widespread pain lasting at least three months, affecting multiple body regions Profound fatigue that is not relieved by rest Sleep disturbances , including non-restorative sleep and frequent waking Cognitive impairment , affecting concentration and memory Mood disorders , such as anxiety and depression Headaches , irritable bowel syndrome, and heightened sensitivity to temperature, light, and noise Diagnosis is primarily clinical, based on patient history and examination, as there are no specific laboratory tests or imaging studies that confirm fibromyalgia

16 This statement recommended that sponsors demonstrate the safety of their products for patients with cardiovascular (CV) disease, as most phase II and III trials excluded such patients

Maiti P, Manna J, Dunbar GL

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