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This study investigated whether semaglutide (SMG) can counteract the disruption to the gut-heart-metabolic axis and associated myocardial injury caused by obesity

GLP-1 and GIP are incretin hormones that help regulate blood sugar and appetite

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We found that removing germline disrupts the cell adhesions between GSC and DTC, causing a significant transcriptomic change in DTC through hmp-2/-catenin and two GATA transcription factors, elt-3 and pqm-1 in this niche cell
