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This mechanism reduces the risk of hypoglycemia when used alone, though this risk increases when tirzepatide is combined with insulin or sulfonylureas

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Syra Hanif M.D

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Dual Hormone Action: Tirzepatide activates GLP-1 and GIP receptors

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It is important to understand what happens next

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While this trial used a lower dose of semaglutide than whats prescribed for weight loss (typically 2.4 mg in Wegovy), the trend remains the same: tirzepatide leads to more weight loss than semaglutide across the board

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