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To begin with, GLP-1 is secreted by L cells in the lower intestine, and its secretory stimuli include nutrients, the gut microbiota itself, and metabolites of the gut microbiota, such as short-chain fatty acids 47,48

[9] Lifestyle shapes your BMR as much as biology Strength training builds calorie-hungry muscle

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Clinical studies provide strong support for these mechanistic insights, showing that GLP-1RA treatment significantly reduces liver fat content (LFC) as measured by imaging modalities and improves biochemical markers of liver injury (17, 18)