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The MHRA approved it on 11 June 2026

[1] While DKA is uncommon in type 2 diabetes and not a direct effect of GLP-1 receptor agonists like Ozempic, it can occur in certain situations, particularly if you are also taking SGLT2 inhibitors or insulin

However, individual patient responses vary, and ongoing monitoring remains appropriate for all patients receiving tirzepatide therapy, particularly those experiencing unexpected changes in treatment response or unusual injection site reactions

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If your weight challenges stem primarily from difficulty controlling portions, constant food cravings, or an inability to feel satisfied after meals, semaglutide targets these specific mechanisms