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Description
Most patients notice appetite suppression within the first few weeks of treatment

Effects of additive therapy with spironolactone on proteinuria in diabetic patients already on ACE inhibitor or ARB therapy: results of a randomized, placebo-controlled, double-blind, crossover trial

The better approach is individualized care that considers metabolic health, lifestyle, medical history, and long-term function
By the time symptoms appear or laboratory values become overtly abnormal, years of damage have already occurred

Caffeinated beverages: While moderate coffee or tea may be okay, excessive caffeine intake can contribute to anxiety and interfere with sleep, worsening other side effects
