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After almost two years of discussions, WTO Members agreed on a compromise that applied only to vaccines and was accompanied by operational limitations that significantly reduced its practical effect.The debate surrounding GLP-1 medicines presents a remarkably similar challenge, but in a less visible context

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The STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial programme demonstrated that adults using semaglutide 2.4 mg weekly alongside lifestyle intervention lost an average of approximately 15% of their body weight over 68 weeks, compared to around 2.4% with placebo. NICE approved Wegovy for use in specialist weight management services in the UK in 2023 (TA875), recognising its clinical effectiveness. Ongoing research continues to explore its cardiovascular benefits, with the SELECT trial showing a significant reduction in major cardiovascular events in people with obesity