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This is consistent with what you typically see in non-GLP-1 studies with weight loss of 20 pounds or more. The researchers also discovered something overlooked: body composition scans measure lean mass, which includes organs like the liver, not just muscle

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Lipodystrophy and nodule formation Subcutaneous nodules can form after GLP-1 injections, particularly with longer-acting formulations

However, another study found no significant correlation between endogenous GLP-1 levels and anticipatory activation for food cues (Perakakis et al., 2021)

Addressing the Root Causes of Weight Gain : My second theory gets to the heart of my biggest concern with these medications