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Liu Q, Anderson C, Broyde A, Polizzi C, Fernandez R, Baron A, Parkes D: Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

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Intracellular signaling, followed by the activation of GLP-1Rs, is mostly mediated through the G s subunit and the activation of adenylate cyclase, which increases the levels of cyclic adenosine monophosphate (cAMP)

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