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While tirzepatide is generally kidney-protective, severe gastrointestinal side effects (persistent vomiting, diarrhea) can cause dehydration that stresses kidney function

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Rejeesh Menon, MD Medical Director, DermaVue Clinics Last reviewed 5 April 2026 GLP-1 Injections FAQ Everything you need to know about GLP-1 therapy for belly fat at DermaVue

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Patients with a History of Eating Disorders GLP-1 medications significantly alter appetite and food intake, which requires careful consideration in patients with a history of eating disorders
