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Smaller prospective trials have reported that participants on GLP-1 therapy experience reductions in Patient Health Questionnaire-9 (PHQ-9) depression scores, with improvements often appearing within 48 weeks of starting treatment
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Uptake assumptions for oral semaglutide 14 mg included 14%, 25%, 50%, 75%, and 100% of the current sitagliptin 100 mg share [35]
