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Nat Rev Endocrinol (2018) 14(10):591604

Compared to GLP-1 RAs, no significant difference was observed in the post-interventional hsCRP levels with SGLT2is (WMD: 1.69

FDA approval for indications in weight management

Heres what they do: Help your body release insulin when your blood sugar is high Reduce another hormone called glucagon that usually increases blood sugar Slow down digestion , so you feel full for longer Send signals to your brain to curb hunger and reduce cravings This multi-action approach is what makes GLP-1 drugs helpful in both type 2 diabetes and weight management If Our Body Already Makes GLP-1, Why Take It From Outside

In light of these results, it would be appropriate to carefully evaluate the introduction of GLP-1 RAs in therapy in people with diabetes who have a family history of thyroid tumors and possibly subject such patients to close thyroid monitoring