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GLP-1 agonists are peptides with high molecular weight, which typically limits milk transferbut direct lactation studies are unavailable

Citations Citations to this article as recorded by Risk of depression with GLP1 receptor agonists use in overweight or obese adults with type 2 diabetes: A newuser, activecomparator cohort study Yu Chang, MingHong Hsieh, PoChung Ju, ChengChen Chang Diabetes, Obesity and Metabolism.2026

The weight benefit is also complementary

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Compared to the use of GLP1-RAs alone, the combination of SGLT2is and GLP1-RAs was associated with a 30% reduction in the risk of MACE, with rates of 7.0 versus 10.3 events per 1000 person-years (HR 0.70