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Conclusions In conclusion, both GLP-1RA and SGLT2-i exert a myriad of cardiovascular benefits for patients with diabetes, obesity, heart failure, and chronic kidney disease

Lixisenatide also showed small but significant benefits for urinary albumin to creatinine ratio (24% vs 24% from baseline to month 24), weight loss (-0.7 kg) and blood pressure (-0.8 mm Hg)

For patients who need to lose closer to 5% of their body weight to manage or prevent comorbidities, Tchang said she would likely try another medication that does not produce as extreme results

Gasbjerg LS, Hartmann B, Christensen MB, et al

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