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Description
as of December 2025

Discussion Our findings in context Tirzepatide demonstrated clinically significant improvements in SBP ranging from 4 to 13 mmHg reduction across the three doses (5 mg, 10 mg and 15 mg) at 40 weeks in the SURPASS clinical program

Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms

Key markers include fasting glucose, HbA1c, lipid panel, liver function, and inflammatory markers

Tirzepatide and GLP-1/GIP Mechanisms
