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In the hypothalamus, GLP-1 receptor agonists activate satiety-promoting POMC/CART neurons while inhibiting hunger-promoting NPY/AgRP neurons

It works by mimicking the actions of glucagon-like peptide-1 (GLP-1), a natural hormone that suppresses your appetite, slows digestion, and keeps you feeling satisfied for longer

These findings strengthen confidence in the use of GLP-1 receptor agonists and tirzepatide, providing valuable evidence for clinical practice and supporting personalized therapeutic decision-making in type 2 diabetes care Professor of Medicine, Head of Diabetes Centre, Institute for Clinical and Experimental Medicine

Working with a personal trainer or dietitian can help tailor calorie intake and macronutrient balance to meet individual fitness goals

I was approved for the medication, and he prescribed it