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In terms of cytokines, IL-17A, which is a strong activator of neutrophils (80), is significantly increased by obesity, and is associated with exacerbation of the pathophysiological factors of asthma in humans and mice (75, 76, 78, 81)

The quality of evidence was determined based on publication bias, indirectness, imprecision, inconsistency, and risk of bias

Potential greater risk for pancreatitis Heavy alcohol use is a major risk factor for pancreatitis (inflammation of the pancreas)

While many of these side effects lessen over time, some users discontinue treatment due to persistent discomfort

Beyond Appetite: Discovering Hidden Opportunities in the GLP-1 Era In just a few short years, GLP-1 receptor agonists have transformed from specialized diabetes medications to household names