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Mechanistically, NKp46/NCR1, a specific marker of NK cells, mediates the killing of human and mouse HSCs through unknown ligands, thus resulting in the attenuation of liver fibrosis [88]
A separate study (111) found liraglutide alleviated sensory deficit after focal cerebral ischemic stroke, which may be related to the improvement of A3-16 deposition as well as secondary damage in the ipsilateral thalamus
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In a phase II trial of semaglutide, no treatment effects on hepatic enzymes or transaminases were observed (data on file)
