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This approval expands the potential patient base and strengthens Novo Nordisks position against rival Eli Lilly, as demand grows for effective obesity treatments amid rising healthcare costs
Hypoxia induces the stabilization of the transcription factors hypoxia-inducible factor-1 (HIF-1) and HIF-2 which is influenced by O 2 -regulated proteins such as prolyl-hydroxylases (PHDs) and factor-inhibiting HIF (FIH) [21]
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