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[Google Scholar] 4.Savino F., Benetti S., Liguori S.A., Sorrenti M., Montezemolo L.C.D

doi: 10.2337/db14-1149
Evidence shows that a high cerebral sensitivity to insulin is related to weight loss (220)

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Your clinician will usually raise the dose stepwise to limit nausea and to help your gut adjust
