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2013;369:145-154) found that intensive lifestyle intervention focused on weight loss did not reduce cardiovascular events in a large cohort of adults with overweight/obesity and type 2 diabetes

Meta-analyses conclude that GLP-1 RAs improve metabolic and hormonal parameters in PCOS, though the direct contribution to live birth rates remains uncertain

These include drugs like: Semaglutide (commonly known as Ozempic or Wegovy) Tirzepatide (Mounjaro or Zepbound) These are usually taken as weekly injections

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Morton JI, Ilomki J, Wood SJ et al (2022) Treatment gaps, 1-year readmission and mortality following myocardial infarction by diabetes status, sex and socioeconomic disadvantage