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Description
Biomarkers 9: 203209, 2004

Melanocytic activation is characterized by hyperpigmentation of the matrix epithelium, secondary to activation of the suprabasal layer melanocytes in the proximal matrix and basal layer melanocytes in the distal matrix, without an increase in the number of melanocytes [1] (Fig

In addition, the constipation can be minimized by increasing fluid and fiber intake, and perhaps using a fiber supplement
Kas yra PT-141

It is associated with sun exposure, pregnancy, and use of oral contraceptives, although it can also be seen in patients without any predisposing factor
