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Description
Both above studies suggest that MTHFR polymorphisms might enhance the environmental risks (low folate intake, traumatic stress at childhood) for MDD via the interaction between genetic and environmental factors

doi: 10.1146/annurev-biochem-061009-102430 88 PopeLEDixonSJ
Genes 12 , 2021 (1856)

Psychiatry Res 215 , 258259 (2014)

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