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Description
During aging, the kidneys undergo progressive hypoplasia, along with macro- and microhistological changes, which are exacerbated by systemic comorbidities such as hypertension, diabetes mellitus, and preexisting renal disease

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However, the complexity of its dose escalation schedule and combination protocols demands careful attention to detail

and their cytotoxic evaluation

6 Risk Factors Multiple studies have evaluated the risk factors associated with the likelihood of acute, chronic, and recurrent HZO (Table 1)
