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2.3.3 Metabolite analysis of BPC157 We analyzed the metabolites of [ 3 H]BPC157 in rat plasma, bile, urine, and feces using the samples collected during the aforementioned extraction and plasma pharmacokinetic studies

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10.3389/fphys.2020.615351 40 HyattH

AlbertiKGEckelRHGrundySMZimmetPZCleemanJIDonatoKAet al

Therefore, by activating this NCOA4-mediated ferritinophagy pathway, Erastin promotes the release of free iron, which in turn amplifies ROS production and lipid peroxidation, resulting in an autophagy-dependent mode of ferroptosis
