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these changes occur both in the plasma and the placenta

The first involves the interaction between one molecule of H 2 O 2 and CAT which leads to the production of Compound I, in which the heme group is oxidized to oxyferryl species [45, 50, 52]

Its potential anticancer effects may be linked to the activation of the NRF2-ARE signaling pathway and its associated cytoprotective properties [155]

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