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Sedeek M, Hebert RL, Kennedy CR, Burns KD, Touyz RM

D.VeldhuisJ

Pathogenic mechanisms of autoantibodies in autoimmune diseases include interaction with cell surface receptors, cell surface binding and lysis, immune complex-mediated damage, binding to extracellular molecules, and autoantibody transfer across the placenta [321]

Nonetheless, given at low doses (150 mg), aspirin selectively inhibits production of thromboxanes, but not prostaglandins, thus decreasing the vasoconstrictive action of thromboxanes

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