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Leptin, secreted by adipose tissue and gastric mucosa in response to energy store availability, binds to the leptin receptors in macrophages, promoting phagocytosis and the production of pro-inflammatory and pro-fibrotic cytokines such as IL-1, Il-18, and TGF- [88]

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BPC-157 drives localised angiogenesis and repair signalling at the injury site
