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216 In addition, PRMT4-catalyzed asymmetric dimethylarginine (ADMA) has been reported to bind to NOS as a ligand, leading to NOS dysfunction, resulting in decreased cerebral blood flow and aggravating AD, which can be reversed by inhibition of PRMT4

Karami Fath M, Babakhaniyan K, Zokaei M, Yaghoubian A, Akbari S, Khorsandi M

For a long time, cobalamin has only been known as a widespread organometallic cofactor to many thermally-driven enzymes that catalyse a wide range of processes essential to living organisms, including humans 3

In Fluorescent Materials for Cell Imaging, Wu F-G, Ed

This effect, depending on the situation may significantly contribute to worsening diseases and infections, and/or increase the risk of subsequent infection, with possible life-threatening implications [93]