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Vascular calcification and advanced glycation end products, or AGEs, provide additional pathways through which arteries may become less flexible

Am J Respir Crit Care Med 188:187192 Bafadhe M, Peterson S, De Blas MA et al (2018) Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials

UPE arises from the electronic relaxation of excited species formed during reactions of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and their derivatives (Pospil et al., 2014)

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