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Furthermore, curcumin reduces pro-inflammatory cytokines gene expression, downregulates ICAM-1 and MCP-1, suppresses NFB induction, procollagen type I, and HMGB1, cyclooxygenase-2, and tissue inhibitor of MP-1 and induces PPAR- and have an effect on inflammation [185]

doi: 10.1002/art.42447 144 JutabhaPKumarVAnzaiNRicePJLightnerJWEndouHet al

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Human -glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat