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Chemical shifts (d) are given in parts per million (ppm), and coupling constants (J) are given in Hertz (Hz)

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Although the pathophysiology of hypertension is extremely complex and multifactorial, and the role of factors such as endothelin, 2 cyclooxygenase-dependent vasoconstrictors 3 and endothelium-derived hyperpolarizing factor 4 needs to be acknowledged, numerous experimental animal studies suggest that this condition is associated with an increased formation of reactive oxygen species (ROS) from all layers of the vascular wall