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Furthermore, metformin enhanced the susceptibility of endometrial cancer cells to chemotherapeutic agents by suppressing the expression of GLO I [164]
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doi: 10.1155/2018/5063185 537 HussainAHussainA
confirmed that the up-regulation of Drp1 induced by high glucose promoted the release of hexokinase-II from mitochondria, which subsequently inhibited the PINK1/Parkin pathway of mitophagy, leading to retinal damage in DR
