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By mapping non-mammalian Au-binding hotspots (e.g., Grx-domain C28-C31), this work established a foundation for designing next-generation inhibitors that exploit parasite-specific structural vulnerabilities, advancing efforts to combat auranofin resistance and improve schistosomiasis therapeutics

10.3390/nu8050248 135 NaeemA.YuC.ZhuW.ChenX.WuX.ChenL.et al (2022)

Crystallization of the TGP-Sb44 complex The TGP construct for crystallization contained residues 1218 of TGP with a C-terminal octa-histidine tag spaced with a (SGGG) 2 linker

These cells protect our skin from UV exposure, infection, and help keep skin hydrated

Phu HT, Thuan DTB, Nguyen THD, Posadino AM, Eid AH, Pintus G