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GSK-3 inhibition supports neuronal survival and may contribute to P21's antidepressant-like effects observed in animal models
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Similar therapeutic effects can also be seen upon direct induction of HO-1 with CoPP which reduces T cell infiltration into the CNS in the EAE mouse model of MS (107), while expression of the enzyme itself is reduced in PBMC from MS patients (108)
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Diseases caused by exposures to mycotoxins is known as mycotoxicosis
