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The role of natural products in targeting cardiovascular diseases via Nrf2 pathway: Novel molecular mechanisms and therapeutic approaches

A list of candidate biomarkers was determined from the proteins that presented a Welch t-test q- value less than 0.05 (after BenjaminiHochberg correction for multiple testing) and from the top contributors in component 1 and 2 of a sparse partial least square discriminant analysis (sPLS-Da) computed with the Mixomics R package 56

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Oxidative stress occurs when our bodies release chemicals (free radicals) in response to internal and external challenges during our lifetimes, such as illnesses, psychological stress, toxins ( mold, heavy metals, chemicals), medications, and poor diet