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Description

Diagnosis: laboratory tests Key diagnostic test: newborn screening The pattern of increased Phe concentrations with reduced Tyr concentrations resulting in elevated phenylalanine/tyrosine ratio detects all forms of HPA in national newborn screening (NBS) programs [38]

Clinical implications: anxiety, depression, brain fog, and mood disorders often have a gut component

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Hypothyroidism symptoms: If an underactive thyroid is the cause, complications like chronic fatigue, weight gain, constipation, and cold intolerance can persist