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PMID: 2682665

Patients with advanced liver disease, cirrhosis, or significantly elevated liver enzymes should not use lipotropics without hepatologist clearance, as impaired hepatic function may alter the metabolism of methionine and choline

Always consult with your healthcare provider before starting weight loss therapy with tirzepatide to ensure safety and effectiveness

Extensive experiments have provided substantial evidence for the effectiveness of various natural substances, such as Polygonum multiflorum, Artemisia annua leaves, berberine (BBR) [13], and curcumin, in alleviating MASLD

Expert Opin Pharmacother (2011) 12(14):221534