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Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors

Alm disso, a GSH atua como cofator de enzimas antioxidantes, como as glutationa peroxidases, que eliminam perxidos perigosos e protegem contra o estresse oxidativo

1) forms the unique structure of cobalamins

Reactions of GSH The most important chemical functionality of GSH is its cysteinyl moiety, which can act as a radical scavenger and reducing agent via its sulfhydryl group (SH) or participate in detoxification reactions through its addition to the electrophilic center of xenobiotics [1]
