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Other dietary approachesincluding low-carbohydrate, ketogenic, or high-protein regimensmay offer benefits in specific subgroups (e.g., individuals with obesity or diabetes), but raise concerns regarding long-term adherence, sustainability, and adverse lipid profiles [146,147]

Apart from enhanced glucose/fatty acid cycling, it has been shown that GH induced insulin resistance is accompanied by reduced muscle glycogen synthase activity (91) and diminished glucose dependent glucose disposal (92)

doi: 10.3390/molecules26206222 169 RamliNZChinK-YZarkasiKAAhmadF

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