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In cases with neoplastic lesions, mice with Grade 3 or 4 lesions were categorized as death by neoplastic disease

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Numerous studies have shown that patients (particularly children) and their caregivers dislike the administration of injections due to needle phobia, the (real or anticipated) pain associated with them, the inconvenience and/or complexity of the regimen (eg, the multiple steps involved in the injection protocol and storage and needle disposal issues) as well as injection site reactions such as bruising (11, 12)

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