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Penz M, Kornek GV, Raderer M et al (2001) Subcutaneous administration of amifostine: a promising therapeutic option in patients with oxaliplatin-related peripheral sensitive neuropathy

Important caveat: there are no completed human clinical trials of 5-Amino-1MQ

In addition, compared with conventional two-dimensional cell culture systems, three-dimensional cell culture systemsbrain organoidsmay more closely mimic the environment of neurodevelopment in the mammalian CNS and thus improve the maturation of iPSC-derived neurons [85,86,87]

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Simultaneously, to ascertain the impact of HT on the migration capacity of HCT116 and SW480 cells, a migration assay was employed (Fig