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Curcumin-attenuated TREM-1/DAP12/NLRP3/Caspase-1/IL1B, TLR4/NF-B pathways, and tau hyperphosphorylation induced by 1, 2-diacetyl benzene: an in vitro and in silico study

pmid:13825279 18

A lower SAMe level could attenuate the suppressing activation of the TLR4/MAPK pathway, therefore upregulating the tumor necrosis factor-alpha (TNF-) expression in KCs (87)

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