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The melanocortin system has a well-established role in the regulation of energy homeostasis but there is growing evidence of its involvement in memory, nociception, mood disorders, and addiction

Int J Mol Sci 23

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Knocking down LAMP2A significantly induces senescence in primary human fibroblasts, as evidenced by increased senescence-associated -galactosidase activity, ROS production and lipofuscin accumulation (132)